Can an estrogen and testosterone combination help treat my hot flashes?

Estratest is a hormone treatment product that combines estrogen and testosterone. It was approved for treatment of hot flashes in women who don't respond to estrogen alone. But the Food and Drug Administration (FDA) has questioned whether there is evidence that Estratest is effective for that purpose.

The company that makes Estratest has told the FDA that it will conduct studies to evaluate the product's effectiveness. In the meantime, Estratest remains on the market despite the FDA's statement that it "does not believe there is substantial evidence" that testosterone contributes to the effectiveness of the treatment. Since there are safety concerns about women using testosterone, the lack of evidence of effectiveness is particularly worrisome.

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