Can I use OPKs if I am taking injectable fertility drugs such as Pergonal, Humegon, Repronex, Gonal-F, Follistim, or Fertinex?

This is a tough one to answer. Pergonal, Humegon and Repronex are made from LH+FSH and may contain enough LH to cause a false reading, though the FSH-only meds, Gonal-F, Follistim and Fertinex, should not effect testing. With any of these drugs, patients should have follicle size monitored by ultrasound and then get an HCG trigger to induce ovulation when the follicles are large enough rather than relying on OPKs.

Many patients do not have a natural LH surge while on injectable medications. Some doctors will ask you to use OPKs in addition to ultrasound monitoring, but be weary of one who goes only by OPKs. More.

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