Can my abdominal fat determine my cardiovascular disease risk?

Abdominal obesity is highly associated with metabolic syndrome, insulin resistance, elevated inflammatory markers, high cholesterol, high triglycerides, high blood pressure, dyslipidemia, and hypertension. It is much more strongly linked to these conditions than body mass index is. So, apparently it is not how much you weigh, but rather where you store your fat, that determines your risk of cardiovascular disease.

Abdominal fat tissue was previously regarded as an inert storage depot; however, the emerging concept describes adipose tissue as a complex and highly active metabolic and endocrine organ. Fat cells secrete adipokines, hormonelike compounds that control insulin sensitivity and appetite. As abdominal fat accumulates, it leads to alterations in adipokines that ultimately promote insulin resistance and an increased appetite, thereby adding more abdominal fat.

Fortunately, reduction of abdominal fat through dietary means and increased physical activity can reestablish insulin sensitivity and reduce appetite.

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