The is a breakthrough in prostrate cancer which uses the body's immune system to fight the disease and just recently received federal approval. This is a good alternative to chemotherapy which is quite taxing to patients. Provenge vaccine helps train the immune system to fight tumors.It is called "vaccine" even though it treats disease rather than preventing it.
Doctors have been trying to develop a therapy for decades and Provenge is the first to got a nod of approval from the US FDA. This is the first immunotherapy who won an approval and can be a stepping stone for creating other immunotherapies against cancer in general. Doctors treat cancer by surgically removing tumors and killing them with chemotherapy drugs or radiation but Provenge offers an alternative approach by directing the body's natural defense mechanisms against the disease.
This treatment is intended for prostate cancer that has spread elsewhere in the body and does not respond to hormone therapy. Medical specialists welcome the approval of Provenge and thought of this as an important milestone but stressed that it will serve as an addition to medical practice and not a replacement. Studies showed that taking Provenge added four months to the lives of men who have advanced prostate cancer.
Dendreon the company who made Provenge spent more than 15 years developing and testing Provenge. In each regimen of treatment, Provenge must be tailored to the immune system of the patient using a time-consuming formulation process. First doctors are going to collect special blood cells from each patient that help the immune system recognize cancer as a threat.
These cells are then mixed with protein found on most prostate cancer cells and other substance to speed up the immune system. The resulting "vaccine" is then given back to the patient in three doses for two weeks apart. The side effects of Provenge are relatively mild like chills, fatigue, fever, and headache.
Provenge is like a vaccine that treats prostate cancer, it works through Immunotherapy which means it increases the effectiveness of the immune system as it attempts to destroy or reject the cancerous cell's. It's made from getting cell's from a patients tumor then mixing it with the patients blood cells and the Dendreon PAP(enzyme produced by the prostate) and GM-CSF(immunity part) fusion protein Unlike other vaccine's it doesn't actually prevent the cancer meaning no, it doesn't prevent cancer, sorry. It is however the first vaccine to actually treat cancer, making it an effective and reasonably safe solution against fighting cancer.It is not a cancer cure but more an effective treatment against it.
According to prostate-cancer. Org, "Provenge is administered in a unique process (see graphic) called leukapheresis in which the blood is filtered, separated, the white blood cells are removed, and a portion retained, with the remainder being returned to the individual. Dendritic cell (DC) precursors are isolated and then incubated with a fusion protein composed of PAP and a DC targeting element.
Patients receive 3 doses, each 2 weeks apart. Provenge belongs to a class of drugs designed to train the body’s immune system to fight cancer.
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