In theory, yes. ATA 133 is backwards compatible all the way to ATA 33. However, if you have trouble, the most likely problem is that the motherboard bios needs an update.
I had this problem on an ASUS MB. The CD drive would appear in the startup/BIOS and I could even boot to the CD-ROM drive to begin to install windows, but once the install got 2/3 done and windows loaded all its drivers, the CD drive would disappear as far as the operating system was concerned. If you are having a similar problem, go to the MB manufacturer's website and update your bios.
WARNING - this can be very risky, since it is possible to kill a Motherboard by installing the wrong BIOS on it.
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