DataBinding to selected TreeViewItem only if child of other TreeViewItem?

You would likely be best served with defining a DataTemplate selector, and creating several datatemplates. The selector can evaluate all kinds of logical rules, and return the template that you want.

I solved this myself by adding an event handler on click for each of the child TreeViewItems I am concerned with. With this I could then get the DataContext from it, and set it to be the DataContext of the TextBoxs, and create my own bindings.

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