Django ORM: Optimizing queries involving many-to-many relations?

I think you've already outlined the two easy possibilities. Either you do a single filter query against Generic and then cast each item to its Specific subtype (results in n+1 queries, where n is the number of items returned), or you make a separate query against each Specific table (results in k queries, where k is the number of Specific types).

Not a complete answer but you can avoid a great number of hits by doing this.

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