Does a dose of zoster vaccine need to be repeated if administered by the intramuscular route instead of the subQ route?

No. Vaccines should always be given by the route recommended by the manufacturer because data regarding safety and efficacy of alternate routes are limited. If a dose of vaccine is inadvertently given by the wrong route, ACIP recommends that it be counted as valid.

There are two exceptions to this recommendation: hepatitis B or rabies vaccine given by any route other than IM should not be counted as valid and should be repeated (http://www.cdc.gov/mmwr/PDF/rr/rr5515.pdf, pages 18-19). More.

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