With some difficulty! You would have to distinguish between devices (no problem - standard techniques apply) and the communication path between devices. For the communication path MTBF, you would need to know which device failures could affect it, and their likelihood.
You also have to decide whether continued communication with a host system is necessary, or whether the system can continue to operate without it. Common-point failures such as a non-redundant power supply might be the major item. With redundant power supplies, the chance of physical damage to the bus might be more important.
MTTR should be estimated on the basis of replacement of failed devices, rather than repair. If a spare device is available, this can be done within a few seconds (as far as the bus connection and communication functions are concerned; physical installation is likely to be the limiting factor). More.
I cant really gove you an answer,but what I can give you is a way to a solution, that is you have to find the anglde that you relate to or peaks your interest. A good paper is one that people get drawn into because it reaches them ln some way.As for me WW11 to me, I think of the holocaust and the effect it had on the survivors, their families and those who stood by and did nothing until it was too late.