How do muscle relaxants compare in treating spasticity caused by a neurological disorder?

Baclofen, dantrolene, and tizanidine are effective treatments for patients with spasticity. When compared to each other, tizanidine and baclofen are similar in their ability to reduce muscle spasms and improve function. There is insufficient comparative evidence both for dantrolene and for the skeletal muscle relaxants which have not been FDA-approved to treat spasticity.

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