How is a mesothelioma diagnosis made?

Sometimes it is hard to tell the difference between malignant mesothelioma and lung cancer. Because of this, a diagnosis of mesothelioma is made after careful assessment of clinical and radiological findings in addition to a confirming tissue biopsy. A review of the patients medical history, including history of asbestos exposure is taken, followed by a complete physical examination, x-rays of the chest or abdomen, blood tests and lung function tests.

A CT scan or MRI may also be done at this time. Diagnostic thoracentesis, in which cells are extracted from the pleural cavity is commonly done, however, in up to 85 percent of cases, the fluid tests negative or inconclusive even though cancer is present. Ultimately, a needle biopsy of the pleura or an open surgical biopsy is required to confirm and determine the stage of the disease.

A biopsy is the removal of cells or tissues so they can be viewed under a microscope to check for signs of cancer. More.

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