How is trastuzumab given (administered)?

Trastuzumab is administered into a vein (intravenous) and the dose depends on several factors, including the size of the patient, the particular treatment regimen being used and the overall health of the patient. During the administration of trastuzumab, particularly the initial infusion, patients may experience chills and fever. Medication to decrease the chances of this reaction occurring may be given prior to treatment with trastuzumab.

In addition, a more serious allergic reaction to trastuzumab may occur, although it is rare, that causes difficulty breathing, closing of the throat, swelling of facial features, hives, chills, low blood pressure, or lightheadedness. Patients should tell their healthcare professional immediately if they are experiencing any of these symptoms. How are patients monitored?

Patients will usually have scheduled meetings with their healthcare provider while they are being treated with trastuzumab. Typically, blood will be drawn to check levels of blood ... more.

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