There are approximately 12 city blocks that equal 1 mile. This can vary from city to city though, with some blocks being further apart, and some being closer together. In New York City 1 mile consists of 20 blocks, and in Washington D.C., 1 mile consists of 10 blocks.
It depends on how large the city block is, as they are not the same size, hence less blocks are needed to make your mile. Also keep in mind that each city block is as big as its' city, with this in mind, it may be safe to say that a city block is approximately 1/16 to 1/8 of a mile.
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