How safe is triptan for treating migraines during pregnancy?

Triptans are among the most effective acute migraine agents. Drug companies continue to collect data in pregnancy registries on women who have used triptans during pregnancy. There is currently no high-quality evidence suggesting an increased risk for birth defects when a triptan was used during pregnancy.

Most women who used a triptan during pregnancy used sumatriptan (Imitrex), and no specific increased risks have been identified. A recent review of available data on sumatriptan treatment concluded that first-trimester treatment of worsening or new-onset migraine is probably safe. Due to the relatively small number of identified women who have used triptans during pregnancy, however, strong safety recommendations cannot be confidently made, and these drugs should generally be avoided during pregnancy.

If you do take a triptan when you're pregnant, contact the drug company to let them know, so that they can continue to collect data on triptan effects during pregnancy.

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