If it's a low-profile model (and most 5450 cards are low-profile ready) then yes, it will fit into the slimline Inspiron 530s case. However the 5450 is a very weak card not intended for gaming, and putting 2gb of RAM on that model is useless. The 5450 isn't fast enough to play at resolutions where more than 512mb is ever used.
A better choice for the Inspiron 530s is the Radeon HD 6450, or better yet the 5570. http://www.newegg.com/Product/Product.as... http://www.newegg.com/Product/Product.as... The power consumption on both cards is low enough to work in most Dell slimlines. However between them, the Radeon HD 6450 draws less power (and is slower).
But it's still far better than a 5450. Performance: http://www.tomshardware.com/reviews/rade... http://www.techspot.com/review/245-ati-radeon-hd-5570/page6.html http://www.xbitlabs.com/articles/graphics/display/gigabyte-geforce-gt430_6.html.
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