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Alopecia or baldness is the general term. Male pattern baldness can affect men and women of any age. There are many thoughts and ideas about it.
Some claim it is testosterone derived, however many geneticists say different. Just look at many Northern European men with high testosterone levels, like Italians or Greeks and they have hair all over but may stillb be bald on top. What we do know is this, there are many different reasons that Alopecia can happen.
Stress, vitamin deficiency, chemical or environmental toxicity. Allergic reactions all can play a part or be the cause. Have you ever noticed when you get stressed out hair will just fall out in clumps or more strands?
Hereditary versions actually affect the hair root bulb itself. Some groups and families have hair that falls out early or turns gray early. Basically it is a slipped gene.
And it is not always pinpointed to any one family side, either maternal or paternal, since recessive genes can be a big part in it on either side. What we do know is there are things that can help prevent the death of a hair root bulb. Products like Rogaine work by keeping the bulb and hair area clean and healthy.
Biotin as an oral vitamin supplement with high B vitamin complex (all B vitamins) has shown to keep hair in place. But there really Is no one genetic side to it.
Baldness is paternal and high levels of testosterone have also been linked to baldness, I'm afraid.
May 27, 2005 -- Mothers may unwittingly put their sons on the path to baldness. Chalk it up to genetics, says European researchers. They include Markus Nöthen, a genomics professor at Germany's University of Bonn.
Nöthen and colleagues say they've found a gene variation that may explain some cases of male pattern baldness (androgenetic alopecia), the most common form of hair loss, which is related to the male sex hormones. The suspect gene variation sits on the X chromosome, which is handed down to men by their mother. So a man may get an idea of his scalp's future from men on his mother's side of the family.
While hereditary factors are an important cause of hair loss, other factors also influence hair growth and loss. A white man's chance of male pattern baldness increases with age; in his 50s, he has a 50% chance of having at least some hair loss, the study shows. "The fact that family studies of male pattern baldness have typically stressed the resemblance of fathers and sons is understandable, given the differences in patterns of hair loss between males and females," write Nöthen and colleagues.
"Our genetic data, however, stress the relative importance of the maternal line in the inheritance of male pattern baldness. Nöthen's team studied 95 families in which at least two brothers had premature male pattern hair loss. The group included about 200 affected men.
Genetic screening showed that the "cardinal prerequisite" for premature male pattern baldness was a variation in the androgen receptor gene. The gene variant was found "very much more often" among prematurely bald men than among men who still had a full head of hair after age 60, says Nöthen in a news release. Androgens are male sex hormones, such as testosterone.
Nöthen's colleague, Alex Hillmer, says the exact mechanisms aren't known, but the gene variation seems to boost androgens' effects, leading to hair loss. Male hormones are responsible for excess body hair, except for on the scalp where excess male sex hormones can lead to baldness. Baldness may also be influenced by other genes, some of which could come from fathers, the study notes.
"We have indications that other genes are involved, which are independent of the parents' sex," says Nöthen. So hair loss could be a father-son inheritance, too.
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