STOP! Decide what cartridge you want to shoot first. Then identify your budget.
Then decide on the style, make and model. So which cartridge do you want to shoot? FN 5.7x28mm is unique, primary designed as a sub machine gun round that (with the right ammo, that is very hard for civilians to get) can defeat body armor.
The ammo is made only by FN and is expensive and not convenient to get. The FN Five Seven is the only handgun that shoots it. For civilian use, it might be a good gun for someone that want to protect themselves from small predators, or do 50 yard pistol target shooting, or has an extra $1000 to blow on a new gun because they have all the other calibers.
Except for the fact it is easy to shoot and realtively low recoil, the cartridge has not practical value for most, especially not a first time gun owner. .45 ACP - A proven handgun cartridge that is more than 100 years old. Every single handgun company has one or more models that use this cartridge.
The big slow bullet penetrates far and creates a large permanent wound channel. The drawbacks are that it generally more expensive to shoot than 9mm and the handgun capacity is lower. Many experience owners rely on this, even low cap carrying 1911 style handguns.
They feel confident with the bullet and since they regularly practice they feel confident that you put the bullet on target and reload quickly, so low capacities don't bother them. 9mm Luger - Probably the most common centerfire handgun cartridge worldwide. Military use it.
Many international police forces use it (US police tend to use .40 S&W or .357 sig). Perfectly capable of defense with proper JHP defensive cartridges. Relatively low recoil and if the ammo supply ever settings down, relatively economical to shoot, and its size gives some handguns up to an 18 round capacity.
Every handgun maker has one or more 9mm models. For a new gun owner who don' t have a reason for a preference, this is probably the best all around choice. Budget?
On your list the Five Seven is a $1000 handgun. The USP is around $850, and the Glock around $600. That's a pretty big spread.
Style/make/model? Do you prefer the single action, striker fired like the Glock and Five Seven. Or do you prefer the DA/SA hammer fired option of the H&K?
If you don't know, the you need to take yourself to the range and decide. I suggest eliminating the Five Seven from your list as being too expensive and the least practical. If you prefer the style of the HK USP, then also consider Sig Sauer, CZ, FN FNX, and Beretta; all of which I think are better values than the USP.
If you prefer the Glock, then also consider Springfield Armory XDm (my preference), Ruger, FN FNS, and S&W M&P. EDIT: Quickest fire rate? They will ALL fire as fast as you pull the trigger.
In a practical sense the Five Seven will be the quickest fire rate ON TARGET due to its low recoil, then comes the Glock 9mm, and then the USP 45. If you really want the quickest fire rate then just get a .25 Auto, the lowest recoil of all. Recoil and the effect on follow-up is something to consider when you choose your cartridge, but as a discriminator between guns it only serves to demonstration you have no idea what you are doing.
You can shoot just about any semiauto pistol really fast if you bump fire it. Quickest aimed shots will probably be the Glock 17, the design of the gun minimizes muzzle flip and decreases time to reacquire sight picture for follow up shots. Of all the handgun i've rented Glocks are the fastest to shoot aimed shots.
I ended up buying a Glock 19, one of the reasons why picked it up. I could fire off 5 aimed shots in rapid succession, faster with a Glock than any other handgun. Not expert, this is just my experience.
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