If you're constantly going back and forth between UI and thread pool threads, your code is going to be a bit messy.
I didn't work with SpreadsheetGear workbook, but I suppose that it has an event mechanism which you could use for storing relevant data for you in a custom object which you can access from the outside of the UISynchronizationContext, in this way you avoid to be strongly bounded to the workbook UI control. This will permit you to avoid blocking UI thread with.
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