In addition to @Marijn s post, depending on your configuration sometimes the exception No persistence exception translators found in container. Covers the real cause. Attaching to your process start and catching all spring.net exceptions (Ctrl+Alt+E / CLR Exceptions) usally reveals the root cause.
You get this error when there isn't an object that implements IPersistenceExceptionTranslator in your container. When you have a Spring.Net+NHibernate application, then this would typically be Spring.Net's LocalSessionFactoryObject. The PersistenceExceptionTranslationPostProcessor inspects the context for registered IPersistenceExceptionTranslator instances.
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