What are the risks involved in using artificial sweeteners?

Saccharin is a known cancer-causing compound in rats. Although these effects have not been noted in humans, it must be pointed out that saccharin has been shown to cause cancer in rats only if it is administered over two generations. Therefore, it might be that future generations may pay for the current consumption of saccharin.

This effect on future generations may finally provide the firm evidence the American Medical Association's Council on Scientific Affairs requires. This council has concluded that "until there is firm evidence of its saccharin's carcinogenicity in humans, saccharin should continue to be available as a food additive." Aspartame is composed of aspartic acid, phenylalanine, and methanol.

Aspartame was approved for food use by the FDA in 1981, despite the final recommendation of the FDA Advisory Panel on aspartame that no approval be granted until safety issues could be resolved. Richard Wurtman, M.D., the pioneer in the study of nutrition and the brain, cautioned the FDA that, based on his extensive research, aspartame could significantly affect mood and behavior. Wurtman and other researchers have demonstrated that aspartame administration to animals, at levels comparable to those of high human consumption, alters brain chemistry.

While the long-term effects of aspartame are largely unknown, some people are quite sensitive to aspartame and report immediate reactions. Some of the problems associated with aspartame ingestion include seizures, migraine headaches, hives, and disturbances in nerve function. Aspartame is particularly problematic for some individuals who suffer from migraine headaches.

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