What are the risks of taking ibuprofen during pregnancy?

Taking nonsteroidal anti-inflammatory drugs (NSAIDs) (ibuprofen, naproxen, diclofenac, and others) early in pregnancy has been linked to an increased risk for miscarriage. The risk is highest when NSAIDs are used around the time of conception. Using them in the third trimester can also have harmful effects on the baby's heart development, contractions of the uterus, and bleeding.

Most doctors in the United States limit NSAIDs to the first and second trimesters, while many European doctors limit their use to only the second trimester because of increased early miscarriage risk. It is safest to restrict NSAIDs to the second trimester only, if they are used at all. Talk to your doctor about whether he or she is comfortable with your use of NSAIDs during your pregnancy.

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