What causes fibrocystic breast changes?

Fibrocystic breast disease (FBD) is apparently the result of an increased estrogen-to progesterone ratio. However, other hormones also play important roles. For example, the changes within the breast in FBD may be due to the hormone prolactin.

Typically, significantly elevated levels of prolactin are found in women with FBD. The levels are higher than normal, but not so high as to cause loss of menstruation (amenorrhea). The increase in prolactin is thought to be the result of higher estrogen levels.

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