There appear to be several different causes of reflux. Genetics seems to be a key factor, but allergies, dietary intolerances, and other digestive disorders also may play a role. Children with asthma, cystic fibrosis, muscular or neurological problems and conditions such as Down syndrome are more likely to have GERD.
From Good Kids, Bad Habits: The RealAge Guide to Raising Healthy Children by Jennifer Trachtenberg.
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