A centrifuge generally uses centrifugal force to separate the desired product, which can either be proteins or nucleic acids, from the suspension made of insoluble fine solids in liquids. The desired product can be either in the supernatant (the clear liquid obtained as a result of centrifugation) or the pellet (residue from centrifugation sedimented at the bottom) A centrifuge uses the idea of centrifugal force by rapidly spinning a sample around many times. This causes the sample, upon completion, to be separated into its highest density components at the bottom of the centrifuge to its lowest density components at the top.
This makes doing certain things easier, like decanting supernatant (liquid) or collecting specific layers from a sample.
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