Systemic response is a medical term which means that your whole body is responding to a physical crisis or trauma or exacerbation of certain diseases (especially inflammatory and autoimmune diseases). There is a medical condition known as systemic inflammatory response syndrome, in which the body reacts to trauma or certain surgical procedures, but no medical term "officially" known just as systemic response syndrome.
I cant really gove you an answer,but what I can give you is a way to a solution, that is you have to find the anglde that you relate to or peaks your interest. A good paper is one that people get drawn into because it reaches them ln some way.As for me WW11 to me, I think of the holocaust and the effect it had on the survivors, their families and those who stood by and did nothing until it was too late.