What is the best antibiotic to cure chlamydia?

The Centers for Disease Control and Prevention recommends doxycycline or azithromycin as first-choice antibiotic for the treatment of chlamydia infection. These medications are very effective for both acute and persistent infections. A recent analysis of 12 randomized clinical trials of azithromycin versus doxycycline for the treatment of genital chlamydial infection demonstrated that the treatments were equally efficacious, with microbial cure rates of 97% and 98%, respectively2.

Doxycycline (Doryx, Vibramycin) Doxycycline is an old proven and reliable treatment with cure rates exceeding 90%. Most new treatments are compared against this antibiotic. However, this medication is contraindicated during pregnancy and breastfeeding.

Doxycycline is less expensive than azithromycin, and it has been used extensively for a longer period. However, its dosage regimen is less convenient. Doxycycline dosage: 100 mg orally twice a day for 7 days for urogenital chlamydial infection (chlamydial ... more.

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