What is the purpose of cerebrospinal fluid (CSF) analysis?

The purpose of a CSF analysis is to diagnose medical disorders that affect the central nervous system. Some of these conditions include: • viral and bacterial infections, such as meningitis, West Nile virus, herpesvirus, and encephalitis • tumors or cancers of the nervous system • syphilis, a sexually transmitted disease • bleeding (hemorrhaging) around the brain and spinal cord • multiple sclerosis, a disease that affects the myelin coating of the nerve fibers of the brain and spinal cord • Guillain-Barré syndrome, an inflammation of the nerves. • Early-onset Alzheimer's disease.

The levels of two substances known as amyloid beta(1-42) and phosphorylated tau in CSF appear to be useful diagnostic markers for early-onset Alzheimer's. CSF analysis is also used in forensic investigations to identify the presence of illicit drugs (e. G.

, heroin) or poisons in the bodies of murder, accidental overdose, or suicide victims. Source: The Gale Group. More.

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