What is the role of vanadium in my body?

Vanadium was named after the Scandinavian goddess of beauty, youth, and luster. It is a controversy as to whether vanadium is an essential trace mineral in human nutrition. Although it has been suggested to function in hormone, cholesterol, and blood sugar metabolism, no specific deficiency signs have been reported.

Some researchers have speculated that a vanadium deficiency may contribute to elevated cholesterol levels and faulty blood sugar control manifesting as either diabetes or hypoglycemia. Making things more difficult is the fact that vanadium exists in five different forms, with the most biologically significant being either vanadyl or vanadate. Since vanadium can be a relatively toxic mineral, its use as a dietary supplement should be limited to dosages reflective of dietary intake (e.g., 500 - 1,000 mcg daily).

The major concern is that excessive levels of vanadium have been suggested to be a factor in manic depression, as increased levels of vanadium are found in hair samples from manic patients, and these values fall towards normal levels with recovery. Vanadium, as the vanadate ion, is a strong inhibitor of the sodium-potassium pump. Lithium, the drug of choice for manic depression, has been reported to reduce this inhibition, too.

There is no established RDA for vanadium and no consistent recommendation for the vanadium content of the diet. Some studies have shown that most ingested vanadium (greater than 95 percent) is not absorbed.

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