Effective therapy to prevent migraine aggravation with your menstrual period is call mini-prophylaxis. Prophylaxis is another word for prevention, so mini-prophylaxis means a short course of a prevention therapy. Menstrual migraines may improve by using mini-prophylaxis with hormonal therapy or standard migraine drugs.
Consider mini-prophylaxis only if your headache diary consistently shows a strong link between migraine aggravation and your menstrual periods: Mini-prophylaxis with perimenstrual hormone therapy: 1.5 mg transdermal estrogen patch worn for 7 days, starting 2-5 days before your period is expected to begin Mini-prophylaxis with standard headache therapies: All medications should be used at standard migraine treatment doses (unless otherwise specified by your healthcare provider) for 2-3 days before the expected menstrual period and during the first 2-4 days of menses. Standard acute headache medications include:Nonsteroidal anti-inflammatory drugs (for example, naproxen sodium550 mg twice daily with food or mefenamic acid (Ponstel) 500 mg three times daily with food)1 mg naratriptan (Amerge) twice daily2.5 mg frovatriptan (Frova) once or twice dailySumatriptan (Imitrex) 25 mg three times dailyStandard headache preventive medications include: Beta-blockers, such as propranolol (Inderal) Antidepressants, such as amitriptyline (Elavil) or imipramine (Tofranil) Calcium-channel blockers, such as verapamil (Calan and Isoptin), and flunarizine (Sibelium; not available in the United States) Neurostabilizing antiepileptics, such as topiramate (Topamax).
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