When during a menstrual cycle are headaches likely to occur?

Headaches typically occur as estrogen levels fall -- occasionally at ovulation or mid-cycle, but more consistently during the days immediately prior to the onset of menstrual bleeding, when estrogen levels fall precipitously. In one study, migraine activity and menses were monitored in 40 women not using hormonal contraception. Migraines were less likely to occur during those phases of the cycle when estradiol levels were increasing, and 40 percent more likely to occur when they dropped before menstrual flow.

Ovulation was not linked to an increased risk for migraine activity.

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