When should I get a chorionic villus sampling (CVS) test?

Because the chorionic villus sampling (CVS) test is an invasive test and carries a very small (less than 1 percent) chance of miscarriage, it's generally performed when there's an indication of risk: if you've had a prior pregnancy that involved a genetic problem, if there's a history of genetic disease in either your family or the baby's father's, if you had an abnormal first trimester screen or nuchal translucency test, or if you will be 35 or older at the time of delivery and therefore at higher risk of having a baby with Down syndrome.

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