Why did outbreaks of severe acute respiratory syndrome occur in some hospital wards but not in others?

Yu IT; Xie ZH; Tsoi KK; Chiu YL; Lok SW; Tang XP; Hui DS; Lee N; Li YM; Huang ZT; Liu T; Wong TW; Zhong NS; Sung JJ Centre for Emerging Infectious Disease, The Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region, China. BACKGROUND: Most documented "superspreading events" of severe acute respiratory syndrome (SARS) occurred in hospitals, but the underlying causes remain unclear. We systematically analyzed the risk factors for nosocomial outbreaks of SARS among hospital wards in Guangzhou and Hong Kong, China.

METHODS: A case-control study was conducted. Case wards were hospital wards in which superspreading events of SARS occurred, and control wards were wards in which patients with SARS were admitted, but no subsequent nosocomial outbreaks occurred. Information on environmental and administrative factors was obtained through visits to the wards and interviews with ward managers or nursing officers.

Relevant information about host factors was abstracted ... more.

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