Why was Buprenorphine/Naloxone Combination Developed?

In other countries where buprenorphine has been available, there were reports of increasing abuse of the medication. Therefore, the US developers worked to find a way of preventing misuse of the medication as much as possible. Since use of the buprenorphine/naloxone combination tablet by injection will cause withdrawal, the likelihood of misuse by out-of-treatment opioid users is greatly decreased.

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