It is beneficial to chew on an aspirin tablet if you are having a heart attack. In fact, 911 dispatchers often tell people to do this while they are waiting for the ambulance to arrive. Most heart attacks are caused by blood clots.
Aspirin prevents platelets in the bloodstream from clumping, an important stage in clot formation. Although aspirin isn't strong enough to break up a clot that has already formed, many people with heart attacks have clots that are forming, dissolving, and then forming again. If you are already taking a full-dose aspirin every day, the extra aspirin won't do much, since you probably already have the maximum platelet-blocking effect on board.
But it won't hurt, either. Keep in mind that painkillers like acetaminophen (Tylenol), ibuprofen (Motrin), and naproxen (Aleve) do not block clot formation. On a related note, you might want to talk to your doctor about your daily aspirin dose.
A large body of evidence suggests that baby aspirin (81 mg) a day is just as good at preventing heart attacks as full-dose aspirin in most people and is less likely to cause bleeding problems. There is some concern that a minority of people have platelets that aren't responsive to low-dose aspirin and need 325 mg, but the evidence for this "aspirin resistance" is very weak.
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