WPF DataGridTemplateColumn with ComboBox Binding (MVVM pattern)?

As default. Kramer said, you need to remove the RelativeSource from your bindings for the SelectedItem and SelectedValue like this (notice that you should add Mode=TwoWay to your binding so that the change in the combobox is reflected in your model).

Thanks for the help all - I finally worked out why I couldn't select the ComboBox items - was due to a mouse preview event handler I had attached to the cell style when I was using a DataGridComboBoxColumn.

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