If you want an intelligent breed and you have a yard and plenty of time, I'd of course say a Doberman, of American lineage. Europeans tend to still be a bit sharp. Another breed is the not- quite- as- intelligent but very trainable dog you might like would be a Dalmatian, but they can be extremely protective of what and who they perceive as theirs.
Great Danes are good, but don't live long and most have rear end weakness, so you're looking at hip problems in about 5 years. Boxers are great dogs with the best family friendly disposition of the smooth coated larger breeds. I would recommend you strongly consider The Boxer first, Doberman second and Dalmatian third.
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