To answer this they first surgically removed the ovaries of young female rats, allowed them to recover, and then injected the rats with a single dose of 5 µg/kg cadmium. One group of rats serving as a positive control instead received a pellet implant releasing 60µg/kg/day estradiol. A third group was injected with both cadmium and the anti-estrogen, ICI-182-780.
Responses in each of these groups was compared to untreated controls, whose ovaries had also been removed. The uterine responses in these animals were examined 4 days later, and the mammary gland responses 4 and 14 days later. At the levels of exposure used in the experiments, there were no signs of overt toxicity, nor alterations in body weight.
Uterine weight increased 1.9-fold in cadmium-treated animals compared to controls. The estradiol positive control also increased relative to untreated control, by 3.8 times. Exposure to ICI-182-780 eliminated the cadmium effect, indicating it is mediated by an estrogen receptor.
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I cant really gove you an answer,but what I can give you is a way to a solution, that is you have to find the anglde that you relate to or peaks your interest. A good paper is one that people get drawn into because it reaches them ln some way.As for me WW11 to me, I think of the holocaust and the effect it had on the survivors, their families and those who stood by and did nothing until it was too late.