Entity Framework Oracle and Sql Server - how to build a database independent application?

There is no way to have single EDMX for both SQL Server and Oracle. EDMX consists of three parts CSDL (entity definition), SSDL (database definition), MSL (mapping between those definitions). SSDL must always target concrete database so you need at least separate SSDL for Oracle and SQL Server and if you are lucky you will not need separate MSL as well (mapping must be exactly same which will probably not happen if you are using any tool to generate the database).

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