Hi I'm wondering if nioxin scalp activating treatment (2) should be left on overnight and washed at the end of the next day? Thanks?

The Nioxin System 2 is a three part system. This includes the Nioxin Cleanser, Scalp Therapy and last the Nioxin Scalp Treatment. I assume this is what you are referring to.

If you are indeed referring to the Nioxin System no. 2 Scalp Treatment, it is a leave in treatment. You would use it just like you would a leave on conditioner.

You do not need to make a special effort to rinse it out of your hair. Simply wait until the next time you wash your hair. There is no need to rinse at a special time.

Apply and simply forget about it. Hope this helps!

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