Is primitive neuroectodermal tumor (PNET) different than Ewing's sarcoma?

Peripheral primitive neuroectodermal tumors (PNET, or more correctly pPNET) start in the bone or soft tissues. Like Ewing's sarcoma they are composed of small-blue-round cells. They differ from Ewing’s sarcoma because they show more developed features of cells associated with the nervous system.

Both have a similar response to chemotherapy. Based on these and other similarities Ewing's sarcoma and pPNET are regarded as closely related members of the same family of childhood cancer tumors. More.

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