The profile score is useful, as an average of all the others, but it does lose information in the process. It is good to describe the changes in Symptom 1&2, Activity, and Wellbeing separately as well as the profile when you are presenting your results. With some chronic conditions it may be hard to get a big symptom improvement, but if wellbeing improves that may be very important to the patient.
Conversely with more acute or responsive conditions treatment may change the symptoms and activity scores dramatically, and the wellbeing may change less because so many social and personal things affect it. More.
I cant really gove you an answer,but what I can give you is a way to a solution, that is you have to find the anglde that you relate to or peaks your interest. A good paper is one that people get drawn into because it reaches them ln some way.As for me WW11 to me, I think of the holocaust and the effect it had on the survivors, their families and those who stood by and did nothing until it was too late.