Should I have a brain autopsy done on my loved one with Alzheimer's?

In order to have a brain autopsy done you need to plan well ahead. Permission forms need to be signed and arrangements made with a brain bank in your area. But there are very good reasons for having an autopsy performed at the time your loved one dies: 1.

To confirm the diagnosis; and 2. To contribute to research on Alzheimer’s disease. In general it is necessary to have the brain collected for examination as quickly as possible, usually within two to four hours after death.

This can be done through whoever will be handling funeral arrangements. It will not disturb the physical appearance of your loved one. Or, it may be something that you and your loved one had long ago decided you will not pursue.

If you do proceed you will be informed whether the physical hallmarks of Alzheimer’s disease were in fact present in the brain of your loved one. You will be told to what extent amyloid plaques and fibrillary tangles were found. This will give you closure that you were in fact dealing with Alzheimer’s disease.

Brain tissue can then be used in research to find a solution to this most vexing and puzzling disease. If you follow this course, you and your loved one will have contributed to what is our highest goal for the future: a world without Alzheimer’s disease.

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