Should I take both glucosamine and chondroitin supplements for arthritis?

A study sponsored by the National Institutes of Health (NIH) confirmed the benefit of taking glucosamine and chondroitin together. "The Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT)" was anticipated to be the definitive study on glucosamine and chondroitin. The study compared taking glucosamine alone, chondroitin alone, and glucosamine and chondroitin together, to placebo and celecoxib (Celebrex) for painful arthritis of the knee.

The results showed that glucosamine and chondroitin were effective when taken alone for the treatment of moderate-to-severe arthritis of the knee. When taken together, they were even more effective, including more effective than celecoxib. The relatively high placebo rate may have made it difficult for the study to detect a statistically significant difference in people with mild symptoms.

Glucosamine and chondroitin also modify the underlying disease process of arthritis because they delay narrowing of the joint space and the degradation of cartilage, as well as stimulating new cartilage growth. For an aging population that is looking for ways to slow or reverse joint damage, this is promising news, indeed.

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