What are ephedra alkaloid dietary supplements (EADS)?

EADS are dietary supplements that contain varying amounts and types of ephedra alkaloids. Alkaloids, in general, are chemical substances that contain nitrogen. Alkaloids often possess strong pharmacological activity and their names usually end in "-ine."

Caffeine, cocaine, morphine, nicotine, and quinine are familiar alkaloids. Metabolife 356 and many other EADS also contain caffeine, which intensifies the supplements' effects. There are at least 40 species of evergreen plants that are members of the genus Ephedra.

The ephedra plant has a pine-like odor and is also known as the joint fir or joint pine. The dried branchlets of the ephedra plant constitute the Chinese herb ma huang. The ephedra plant contains from 0.5% to 2.5% alkaloids, of which two are clinically important: ephedrine and pseudoephedrine.

How do I know what ingredients are in EADS? It is difficult to be certain, even when the ingredients are identified on the product's label. Bill J.

Gurley and others studied the ... more.

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