What have we learned from the Human Genome Project?

Space may be the final frontier, but human biology is the original unknown, challenging us to discover who we are and where we came from. DNA, the building block of life, contains the genetic code that informs so much of who we are. This code is written with four letters, each representing a different base.

The four bases are adenine (A), which pairs with thymine (T), and cytosine (C), which pairs with guanine (G). Scientists have long known that these four letters provide the recipes for proteins, which carry out numerous bodily functions. But there are still questions to be answered, including how the 3.2 billion base pairs contained in the human genome are ordered.

(The human genome is a person's entire bundle of DNA divided unevenly among 23 pairs of chromosomes.) To that end, the Human Genome Project (HGP) was launched in 1990. Some of the project's ambitious goals included: • Sequencing the entire human genome • Identifying human genes • Charting variations across human ... more.

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