When a dog gets Cushings disease it is making to much adrenal hormone. There are two reasons that it could happen. They are a tumor of the adreanal gland and a stimulation of that gland that causes it to produce to much.
Cushing's disease is a rare hormone disorder that normally affects people ages 20-50. Those who are overweight or have untreated type 2 diabetes are more likely to get this disease. You can find more information here: endocrine.niddk.nih.gov/pubs/cushings/cu....
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