What is "estrogen dominance" and what is its relationship to progesterone?

Estrogen dominance (a term first proposed by Dr. John R. Lee) is a situation in which there is too much estrogen in relation to progesterone. When a woman fails to ovulate, progesterone cannot reach the optimum 20 - 25 mg.

During the final two weeks of a woman's monthly cycle. This allows estrogen to go unopposed the entire month and upsets the normal progesterone/estrogen balance. During his 30 years clinical practice, Dr. Lee discovered that estrogen dominance was responsible for a number of unpleasant side effects in his patients, among them: bloating, water retention, breast tenderness, and depression.

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