What is the cause of narcolepsy in subjects with normal hypocretin levels or with strong tendency to have narcolepsy running in their family?

We look at the hypocretin genes of many cases who had a strong family history and found no mutations. Other genes and systems must be involved. What is the role of hypocretins in regulating normal sleep?

Some results suggest a role of hypocretins in regulating appetite and general body energy. We need to better understand the connection between sleep, energy metabolism, feeding and hypocretins in narcolepsy. TalkAboutSleep: Thank you, Dr. Mignot, for your comments.

We look forward to more breakthroughs from your team in the future. More.

I cant really gove you an answer,but what I can give you is a way to a solution, that is you have to find the anglde that you relate to or peaks your interest. A good paper is one that people get drawn into because it reaches them ln some way.As for me WW11 to me, I think of the holocaust and the effect it had on the survivors, their families and those who stood by and did nothing until it was too late.