What is the difference between methadone and buprenorphine?

Methadone and buprenorphine (brand name Suboxone) are both opioid agonist approved by the FDA for treatment of opiate dependence. Methadone is only available in registered methadone maintenance treatment clinics regulated by federal and state governments. Treatment usually involves nearly daily reporting to clinics to pick up the day's dose of methadone.

Buprenorphine is available through doctors specially trained and licensed by the DEA. It it can be obtained in the privacy of a physician's office and regulations about it's use are much less strict then for methadone. This allows for greater treatment flexibility for the physician and patient.

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