What is the most important dietary supplement to prevent CVD?

Of all the nutritional products that can help prevent CVD (cardiovascular disease), the most important, without question, is pharmaceutical-grade fish oil. The concept that eating fish may reduce the risk of heart disease began in the 1970s, when it was noted that among the Eskimos in arctic Greenland, where high consumption of marine animals was the normal diet, heart disease was very low. Subsequent studies in similar cultures where fish and seafood consumption was high showed the same sort of protection.

For example, the inhabitants of the Japanese island of Okinawa, who eat primarily fish, were also observed to have a very low incidence of mortality from heart disease.To assess the protective effects of fish against heart disease, researchers conducted large studies in which they tracked dietary intake of fish and other seafood over a long time. As the results of these studies became available in the mid-1980s and 1990s, they provided even stronger evidence that higher levels of fish consumption were associated with a lower risk of mortality from heart disease.It is now estimated that individuals whose diets include a higher intake of fish oils, or who take fish oil supplements, can reduce their risk of heart disease or stroke by roughly 47 percent compared with individuals who do not eat fish or take fish oil supplements. In fact, the level of omega-3 fatty acids in the red blood cells (the omega-3 index) has been shown to be the most accurate predictor of the risk of heart disease and stroke.

It is a more sensitive indicator than other well-recognized markers, including cholesterol, LDL, HDL, CRP, and homocysteine. An omega-3 index of at least 8 percent is associated with the greatest protection against CVD. Scientists now know that fish oils can also lower the risk of many cancers - particularly breast, prostate, colon, and lung cancer - and many other chronic diseases, including Alzheimer's disease, asthma, depression, diabetes, high blood pressure, macular degeneration, multiple sclerosis, and rheumatoid arthritis.

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